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Dosing and Administration
Refer to the Prescribing Information for complete and up-to-date dosing and
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· As First Opioid Analgesic: 10 mg every 12 hours
· In Opioid Non-tolerant Patients: 10 mg every 12
hours
· Conversion from Other Oral Opioids to
Hydrocodone ER: According to the Prescribing Information, conversion (not
equianalgesic) doses for other opioids when switching to hydrocodone 10 mg are
as follows: oxycodone 10 mg; methadone 10 mg1; oxymorphone 5 mg; hydromorphone
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Conversion from Transdermal Fentanyl to Hydrocodone ER: Hydrocodone ER
treatment can be initiated 18 hours following the removal of the transdermal
fentanyl patch. Although there has been no systematic assessment of such
conversion, a conservative hydrocodone dose, approximately 10 mg every 12 hours
of hydrocodone ER, should be initially substituted for each 25 mcg/hr fentanyl
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